Probiotic is OTIC MICROORGANISMS 1.1 DEFINITIONS Yuan Kun Lee Department of Microbiology, National University of Singapore, Singapore “Probiotics” is derived from Greek and means “prolife.” It has been redefined throughout the years as more scientific knowledge and better understanding on its relationship between intestinal health and general well-being has been gained. The following are definitions of “probiotics” derived through times. Lilly and Stillwell in 1965 (5) defined probiotics as “Growth promoting factors produced by microorganisms.” Parker in 1974 (7) suggested an interaction between microorganisms with the host: “Organisms and substances with beneficial effects for animals by influencing the intestinal microflora.” Fuller in 1989 (3) defined it as “A live microbial feed supplement which beneficially affects the host animal by improving its intestinal microbial balance.” Havenaar and Huis Int Veld in 1992 (4) said probiotics are “A mono- or mixed culture of live microorganisms which, applied to animal or man, affect beneficially the host by improving the properties of the indigenous microflora.” ILSI (International Life Sciences Institute) Europe Working Group (1998) (9): “so what is impact on health?

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