In communication with Mehmet Cankaya, we consider the subject.

There is known result of D. Gale and H. Nikaido, The Jacobian matrix and the global univalence of mappings,

Mathematischen Annalen 159 (1965) 81-93.

For simplicity we will consider $2$- dimensional case. Let $D=(a,b) \times (c,d)$ and suppose that $F=(f_1,f_2)$ is $C^1$ on $D$.

Suppose that (i) $D_1f_1= f_{11}\neq 0 $ and $det F' \neq 0$ on $D$.

We outline a proof that (i) implies (I) $F$ is injective on $D$.

Let $c\in F(D)$ and let $F(a_1,b_1)=c$. Find solutions of equation $F(x,y)=c=(c_1,c_2)$ on $D$.

Consider (2) $f_1(x,y)=c_1$. We will  show that the set $f_1^{-1}(c_1)$ is graph of a function. Since $f_{11}=D_1f_1 \neq 0 $ on $D=(a,b) \times (c,d)$ we can suppose that $f_{11}> 0 $. Then (a1) the function $f_1(x,y)$ is increasing in $x$ for every fixed $y$; then there exists an open set $U$ containing $a_1$, an open set $V$ containing $b_1$, and a unique continuously differentiable function $g: V \rightarrow U$ such that $f_1(g(y),y)=c_1$, $y \in V$. Using continuity we can extend $g$ on $(c,d)$ such that $g \in C^1(c,d)$.

Thus there is a function $x=g(y)$, in a

$y \in (c,d)$ such that

$f_1(g(y),y)=c_1$, $y \in (c,d)$. By (a1), $\Gamma_g= f_1^{-1}(c_1)$, where $\Gamma_g$ is the graph of $g$ over $(c,d)$.

Hence (3) $f_{11}(g(y),y) g'(y) + f_{12}(g(y),y) =0$, $y \in (c,d)$.

Let us show that equation $h_2(y)=c_2$ has a unique solution on $(c,d)$. Contrary suppose that $h_2(y_1)=h_2(y_2)$ for $y_1\neq y_2$. Then there is

$y_0$ such that $h_2'(y_0)=0$. Hence (4) $f_{21}(g(y_0),y_0) g'(y_0) + f_{22}(g(y_0),y_0) =0$. Since $det F' \neq 0$, from (3) and (4) it follows that $g'(y_0)=0$ and

therefore $f_{12}(g(y_0),y_0) = f_{22}(g(y_0),y_0) =0$, which is a contradiction.

It seems that using a modification of the above proof we can get a corresponding version  of this  result   for convex sets in n-dimensional space.

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