What is most effective Software /Data Base to Check variations and SNPs in Human genome (e.g, To check some unknown Variations in B catenin gene)?

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Umar Mushtaq

Dear Mohsin M

please try http://www.ncbi.nlm.nih.gov/projects/SNP/

Also try software's like SIFT, PolyPhen, PENTHER, I-mutant2.0

As you said great number of changes you observe, please do check your sequencing conditions like enzymes etc.

Hope helpful.

Cheers

Mohsin Maqbool

Dear Qazi Mohammad Sajid Jamal and Dear

Umar Mushtaq ............Thanks a lot for your suggestions

More valuable suggestions are welcomed.!! thanks

Helen Latsoudis

Dear Moshin

I find the Genomic Variants section of GeneCards quite useful. It contains variants and information from the NCBI SNP Database, Ensembl, PupaSUITE and DNA2.0, with descriptions from UniProtKB, Linkage Disequilibrium images from HapMap, Structural Variations (CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from HGMD, The Human Cytochrome P450 Allele Nomenclature Database, the Human Genome Variation Society's Locus Specific Mutation Databases (LSDB), and BGMUT.

Hope it helps