Is there a threshold by which 24-hr Blood Pressure needs to be reduced by to be clinically relevant?
or is it possible to use the clinic-based blood pressure thresholds?
any papers would be appreciated.
CLINICAL SIGNIFICANCE OF BLOOD PRESSURE REDUCTION IS DIRECTLY CONGRUENT TO THE PATIENT'S PROGNOSTIC WELL BEING. NORMALLY THE GIVEN PARAMETERS SHOULD BE CLOSELY WATCHED AND MAINTAINED DUE TO THE PRESCRIPTION GIVEN. MEDICINE SHOULD BE WITHDRAWN WHEN THE GOALS ARE ACHIEVED.
'For each 10 mm Hg increase of 24-h SBP , there was a hazard ratio (95 % confidence interval) of 1.33 (1.22-1.44) for stroke, 1.19 (1.13-1.26) for cardiovascular mortality, 1.12 (1.07-1.17) for total mortality and 1.17 (1.09-1.25) for cardiac endpoints. '
Article Blood Pressure Control and Primary Prevention of Stroke: Sum...
Lovely article with clear explanations
24 hr ambulatory BP test is an excellent tool, but not always available in resource limited countries.
Also, do not forget the J shaped effect on BP reduction: too low and then the morbidity and mortality risk goes up again.
We are in need of another measure in 24 hr BP graphs: eg: Area under the curve, or index
In search of the ideal BP....
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