Can anyone help me identify the proteins from the mass spectra?

In order to see the binding of a drug to proteins of interest, I used DARTS assay. In the 1D gel, one lane was loaded with crude protein sample and the other lane was loaded with crude protein...

01 February 2018 8,046 4 View

Labs in India where protein-drug interaction studies are possible?

I would like to check the physical interaction between a protein and drug in vitro. Can anyone suggest the best method to study protein-drug interaction and where in India I can outsource this...

05 June 2017 2,453 2 View

Which is the most cost effective way to study Protein-drug interaction in vitro?

I need to analyze the interaction/binding of a drug to a protein. Protein overexpression and purification seem to be every expensive. Is there any way I can study protein-drug binding/interaction...

03 April 2017 4,659 3 View

Anyone would like to share SK-N-SH or SH-SY5Y cell line in India?

My lab would like to procure SK-N-SH or SH-SY5Y cell line. Thanks in advance.

10 November 2016 7,921 2 View

What the possible type of contamination is this?

The following (picture) unknown organism has contaminated our SH-SY5Y cell line, any idea what it is? They are only there in the flasks with cells, not in flasks with culture media alone.

08 September 2016 1,691 7 View

How to do a Protein-Drug-Protein MD Simulation?

I have Protein A, Protein B and a Drug (small molecule). Protein B is an enzyme which can bind to protein A and can hydroxylate it. During docking study, my drug bound to Protein A binding site of...

04 May 2016 2,739 4 View

What should be the SH-SY5Y cell density for doing MTT assay after Oxygen Glucose deprivation?

11 December 2014 1,467 6 View

No title

Does error (difference of less than 3 degree Celsius) in annealing temperature have any role in getting a higher Cq/Ct?

08 September 2014 9,325 13 View

Can anyone help with RNA isolation from Neuroblastoma cells?

07 August 2014 4,350 4 View

Meta-analysis: Data analysis part?

Currently I am working on a systematic review with meta-analysis. I will be writing review about the neuroprotective efficacy on a drug. From the extracted papers I collected infarct volume and...

07 August 2014 3,576 12 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

Can we classify HV and LV lines based on line length?

I have dataset which shows the length of power lines. I need to classify the lines based on the line length. Is there a rule to classify the High voltage (HV) and low voltage (LV) lines based on...

03 March 2021 4,116 4 View

What kind of fluid could I use for a pitfall trap that also does not invalidate molecular testing?

Hi, I want to start testing pitfall trap to obtain ants samples, but I need to conduct molecular analysis on those insects. So, what kind of fluid can I use? Ethanol expires too early and I need...

03 March 2021 5,978 5 View

Anyone plz suggest relevant topic for research in image processing+Deep learning.?

I have selected brain tumor images ...but now found that already lots of research done n this topic.

03 March 2021 5,774 3 View

Irradiation data for JAPAN?

Hi, Could you help me to get the latest (2019, 2020) solar resource data for a particular site in JAPAN? PV GIS and NSRDB data are not in reach to JAPAN, I'm looking for some other database for...

03 March 2021 961 3 View