UP-PCR (Universally Primed) uses only one primer dimer (sequence of 10 nucleotides). Also expect many bands (amplification). Scoring the bands for genetic polymorphism is tediuos for large number of samples. One more thing, the PCR reaction may take longer (3-4 hours) to complete the reactions.
I don't know reason of that but I mistakenly ordered both forward primer instead of one of each but I didn't know I did PCR got two bands 300bp and 100 but originally product size was 450.