In the field of molecular biology, the peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes.[1] PPARs play essential roles in the regulation of cellular differentiation, development, and metabolism (carbohydrate, lipid, protein), and tumorigenesis[2] of higher organisms.[3][4]

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]

PPAR is a peroxisome proliferated activated receptor (nuclear receptor protein) which is a target of type II diabetes

Many thanks for your comments , but still i didnt get  the answere. If asituation leads to expression of PPAR gama, except styding the gene expression by RT - pcr, could it be possible to measure circulatary protein product of this gene?

There is a report indicated the presence of PPARg circulating in exosomes.

http://www.ncbi.nlm.nih.gov/pubmed/19028452

dear Mark Christian,

 I thank you so much for  your valuable comment and link.