I have generated a lot of annotated cancer mutation data by NGS data analysis.
What different kind of bioinformatics analysis can be carried out on that annotated mutation data to get some useful and valuable E results?
I am looking for explanation in the context of NGS variant calling pipeline
27 May 2020 977 1 View
From total number of ovarian cancer cell lines present, for how many cell lines, sequencing data is available?
04 May 2020 3,829 2 View
Consurf server gives output in number of different ways. But I want result in following format, displayed in image? How to get this?
03 March 2020 3,181 1 View
I have used Swissmodel, MODELLER, Phyre, Robetta and I-TASSER for modelling my protein, but in the modelled structure, amino acid is not observed at a specific position to which I want to induce a...
16 January 2020 3,987 1 View
I have created docked complex.pdbqt file using Autodock and I have uploaded that file in Pymol and visualized formed hydrogen bonds between ligand and protein, but the binding site residues of...
27 March 2019 1,482 11 View
Hiiiii everyone! I have an enquiry on statistical analysis. I was looking for many forum and it's still cannot solve my problem. I want to compare means of two groups of data but only with two...
03 March 2021 8,796 3 View
I am on the lookout for the Enhanced Yellow Fluorescent Protein (Aequorea victoria) DNA sequence. Does anyone know where I can find it? Thank you in advance
03 March 2021 3,568 1 View
Hi, I want to start testing pitfall trap to obtain ants samples, but I need to conduct molecular analysis on those insects. So, what kind of fluid can I use? Ethanol expires too early and I need...
03 March 2021 5,978 5 View
What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10? Since, the growth curve from day 2 to 10 won't be like the "Logistic curve" it might not follow logistic...
03 March 2021 1,401 3 View
I have conducted and published a systematic review and meta-analysis research with the topic related to public health and health pomotion (protocol was registed in PROSPERO). Now we want to...
03 March 2021 8,920 3 View
dear community, my model is based feature extraction from non stationary signals using discrete Wavelet Transform and then using statistical features then machine learning classifiers in order to...
03 March 2021 6,994 5 View
1. What is the impact of having different scales in a survey? and how can we solve this problem before and after data collection (Literature-based reflection)? Thank you for your time and for...
03 March 2021 2,870 3 View
I'm dealing with a mediation model and am using the PROCESS module in SPSS. Due to SPSS and PROCESS being limited in the imputation methods - being unable to handle multiple imputation - the other...
02 March 2021 4,362 1 View
I just wanted to check if I need to run a linear regression separately if I am using PROCESS MACRO to run mediation analysis. Thank you.
02 March 2021 4,359 3 View
If the detection range is in ng/ml but the reference range is in ug/ml for a molecule or protein in serum or plasma .how to dilute and what is the initial volume to be taken for quantitative analysis
02 March 2021 7,670 3 View