In an effort to better understand the neurological sequalae of electrical injury, I seek neuro imaging methods for what is historically not seen on standard imaging.
Repeated exposure to high electric fields can theoretically cause acquired channelopathies, perhaps NaMRI combined with mpMRI would work to clarify electrical injury's neural network sequalae.
I've yet to see a study using these mixed methods to look at people with a history of electrical injury. So far I've identified mpMRI coupled with NaMRI as possibilities.
[i] Felker, E. R., Dregely, I., Chung, D. J., Sung, Kyunghyun Osuagwu, Ferdnand C. Lassman, C., Sayre, J., Wu, H., & Lu, D. S. (2017). Irreversible Electroporation: Defining the MRI Appearance of the Ablation Zone With Histopathologic Correlation in a Porcine Liver Model. American Journal of Roentgenology, 208(5), 1141–1146. https://doi.org/10.2214/AJR.16.17207
[ii] Hjouj M, Last D, Guez D, Daniels D et al. MRI study on reversible and irreversible electroporation induced blood brain barrier disruption. PLoS One. 2012;7(8):e42817.
[iii] Hjouj M, Lavee J, Last D, Guez D et al. The effect of blood flow on magnetic resonance imaging of non-thermal irreversible electroporation. Sci Rep. 2013; 3: 3088.
[iv] Madelin, G., Lee, J.-S., Regatte, R. R., & Jerschow, A. (2014). Sodium MRI: Methods and applications. Progress in Nuclear Magnetic Resonance Spectroscopy, 79, 14–47. doi:10.1016/j.pnmrs.2014.02.001
[v] Wimmer T, Srimathveeravalli G, Gutta N, Ezell PC, et al. Comparison of simulation-based treatment planning with imaging and pathology outcomes for percutaneous CT-guided irreversible electroporation of the porcine pancreas: a pilot study. J Vasc Interv Radiol. 2013 Nov;24(11):1709-18.
I'm interested in your thoughts.
- Badges
- Science topic
- Similar topics
- Physical Sciences
- Materials Science
- Plating