Is there any tool or package to prepare input files for Circos from NGS data?

Any tool or package to prepare input files for Circos visualization of NGS data? I know of some, but not very user-friendly.

08 September 2018 9,535 4 View

Variant discovery for variation in quantitative traits between two lab selected populations (4 replicates) from pooled genome sequencing?

Is it possible to discover the variants responsible for variation in quantitative traits between two laboratory selected populations by pooled whole genome sequencing? If yes, how? Also, keep in...

08 September 2018 8,998 12 View

What is the best way to find out which gene a nucleotide belongs to if I have the chromosomal location of that nucleotide?

I have list of some nucleotide positions after an analysis, I need to find out which genes those nucleotides belong to. This could be done in UCSC, DAVID etc, but remember, I do not have a range...

01 February 2018 6,294 11 View

How to download a set of genes from any study/report for analysis in DAVID and PANTHER (For practice purposes) ?

I need to download any gene set to analyze them in DAVID and PANTHER as part of a course. Most of the database are not giving tab delimited text files to put into DAVID or PANTHER.

04 May 2017 9,844 3 View

Any suggestions before buying YASARA Structure package to be used mainly with Transmembrane Ion channels (modeling and MD mainly)?

I am thinking of buying YASARA Structure package to use it for Transmembrane ion channel homology modeling, MD simulations etc. I was wondering if someone can help me with understanding this whole...

02 March 2015 5,793 11 View

How can I measure intracellular Cadmium, Strontium and Arsenic concentration?

I want to measure the uptake of Cadmium, Strontium and Arsenic by cells. I want to do it in live cells mainly, so it will be better if someone can suggest any methods involving microscopy. Any...

11 December 2014 8,507 9 View

What can I use to permeabilize the vitelline membrane of a drosophila embryo, besides D-Limonene?

What can we use except D-limonene? It's basically an organic solvent, but the permeability is actually about the waxy layer (~5 nm) surrounding the vitelline membrane. Would acetone be right for this?

04 May 2013 4,612 13 View

After a reference from Int J Body Compos Res, can any body help?

Hi, I am after the reference below, my library says it cannot obtain a copy either locally or internationally, any help appreciated! Chris Wang ZM, Heshka S, Wielopolski L, Pi-Sunyer FX, Pierson...

03 March 2021 6,193 1 View

New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before?

Question to you and THEM, the New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before? There appears to be a core problem for...

02 March 2021 3,024 2 View

Does anyone have a recommendation for yeast reporter gene plasmid/protocol?

Hi, could anyone recommend a plasmid and/or protocol for reporter gene assay in S. cerevisiae? I want to assess the effect of growth conditions on a transcription factor, so I want to clone it`s...

01 March 2021 210 1 View

Does anyone know HRM channel in a 2 plex QIAGEN Rotor- Gene Q qPCR can be used as a separate channel?

I am going to have 3 different probes in my qPCR work that I am going to do. But I realized that the machine we have in the lab is a Rotor-Gene Q 2plex HRM Platform, saying it has green, yellow,...

01 March 2021 8,544 1 View

No title

01 March 2021 3,905 5 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

Where to find data on trees in tropical agroforestry?

Hi, I'm looking for data (mainly related to management: growth rate, canopy size, soil and climate preferences, etc.) about tropical trees used in tropical agroforestry. Have you ever heard about...

28 February 2021 7,356 8 View

Which group formation theory do you recommend for projects that aim to bring together entrepreneurs for training for regional development?

I would like to have ideas about which theories of group formation are suitable for entrepreneurial training projects, with the aim of creating bonds, building trust, and collaboration for...

28 February 2021 4,223 2 View

What is the most common number of epitopes in an multi-epitope Vaccine?

hi everyone, I'm interested in the field of vaccine design specifically multi-epitope cancer vaccines , I want to know if there is a minimum and maximum number of epitopes we could use in a...

27 February 2021 3,882 3 View