We are using organ bath to study the characteristics of aquaporin, therefore we need specific blockers of smooth muscle and endothelial aquaporin (AQP-1 and AQp-4).
could you please look at this paper (Inhibition of aquaporin-1 and aquaporin-4 water permeability by a derivative of the loop diuretic bumetanide acting at an internal pore-occluding binding site.).
I think bumetanide is the best blocker of aquaporin-1 and aquaporin-4.