If we need to confirm whether vitamin C functions properly under a given clinical condition, what are the parameters to be considered in the case of human subjects? (Usually, it is custom to measure the vitamin C in plasma and intracellular compartments). Additionally, what is the significance of intracellular RBCs' Vitamin C content? (i.e. Suppose that intracellular RBC vitamin C level is decreased in a given clinical condition, can it affect any functions at systemic level?)
Thanking you in advance for sharing your experience.
Dear Annadurai
Please read this review article entitled "Vitamin C in Disease Prevention and Cure: An Overview"
Best Regards
Dear Annadurai,
As you mention intracelluar vitamin Clevels in RBC effect on different functions, it can be of interest for you to do interaction analysis betweeen different biomolecules and cells with different vitamean C levels and see how that affect interaction properties such as kinetics and affinty.
Check the attached papers.
Best regards
Teodor
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