Are there any Organizations or Institutions performing in vivo anti-tubercular assay in India..?

Hi All: I would like to request you all to let me know the information about any organizations or institutions which perform in-vivo anti-tubercular assay of synthetic compounds as a part of...

31 December 2018 4,743 0 View

Can one depend on Grindstone Synthesis in Organic Synthesis...?

Do anyone know about Grindstone synthesis for the synthesis of organic molecules? Some of the researchers are not confident about the process and few are working only on grindstone synthesis as...

31 December 2018 260 3 View

Apart from monitoring TLC & Spectral analysis during the reaction, are there any other methods to determine completion of reaction..?

While running a chemical reaction, one will use either TLC monitoring or Spectral analysis to confirm the completion of the reaction. Are there any other methods apart from TLC and spectral...

07 August 2018 1,253 2 View

Is it possible to get yield more than 100% in a chemical reaction....?

Is it possible to get yield of a chemical product more than 100%...? If so, how one can defend this situation? I am working on Condensation reactions using organic solvent free synthesis. For some...

05 June 2018 365 17 View

Do anyone worked on conversion of p-aminosalicylic acid to its hydrazide..?

If any researcher worked on p-aminosalicylic acid and its derivatives, kindly let me know a simple method to convert p-aminosalicylic acid to its hydrazide form, i.e., 4-amino-2-hydroxybenzohydrazide.

04 May 2018 2,622 3 View

Why Methyl-4-aminosalicylate is not reacting with benzaldehyde....?

I am running a synthetic step to get Schiff's base today. Methyl-4-aminosalicylate and benzaldehyde (in 1:1 molar ratio) in presence of 2-3 drops of acetic acid and absolute ethanol as solvent...

04 May 2018 3,130 24 View

Could any Researcher kindly let me know the simple and most atom efficient synthetic procedure for Schiff bases of p-Aminosalicylic acid?

I would like to request the Researchers to let me know any procedures or references to carryout synthesis of Schiff bases of 4-Aminosalicylic acid when treated with different substituted...

02 March 2018 3,149 10 View

What happens when the following events are noticed in Human Being?

What happens when: 1. HMGCS2 Expression is enhanced....? 2. PfA-M1 aminopeptidase is inhibited....? 3. Mcl-1 is antagonised (inhibited).....? (All these have been estimated using in-silico...

11 December 2016 1,987 5 View

How to separate E and Z isomers?

I had synthesized a compound having two side chains, each side chain is having a Schiff's base (>C=N-), so there will be chance of having 4 isomers. Which will be the best method to separate...

11 December 2016 6,328 5 View

How can I prepare Benzophenone hydrazone using 99% Hydrazine hydrate?

How to prepare Benzophenone hydrazone by reacting benzophenone with 99% hydrazine hydrate? Methods are there preparation of Benzophenone hydrazone from benzophenone and anhydrous hydrazine and...

03 April 2015 1,369 9 View

error in running a model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

17 August 2021 0 0 View

error in modelling model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

17 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MGL tools

20 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

i have some problem with chtMultiRegionSimpleFoam

--> FOAM FATAL ERROR: Maximum number of iterations exceeded From function Foam::scalar Foam::species::thermo::T(Foam::scalar, Foam::scalar, Foam::scalar, Foam::scalar (Foam::species::thermo::*)(Foam::scalar, Foam::scalar) const, Foam::scalar (Foam::species::thermo::*)(Foam::scalar, Foam::scalar) const, Foam::scalar (Foam::species::thermo::*)(Foam::scalar) const) const [with Thermo = Foam::hConstThermo >; Type = Foam::sensibleEnthalpy; Foam::scalar = double; Foam::species::thermo = Foam::species::thermo >, Foam::sensibleEnthalpy>] in file /home/ubuntu/OpenFOAM/OpenFOAM-4.1/src/thermophysicalModels/specie/lnInclude/thermoI.H at line 66. FOAM aborting #0 Foam::error::printStack(Foam::Ostream&) at ??:? #1 Foam::error::abort() at ??:? #2 Foam::heRhoThermo >, Foam::sensibleEnthalpy> > > >::calculate() at ??:? #3 Foam::heRhoThermo >, Foam::sensibleEnthalpy> > > >::correct() at ??:? #4 ? at ??:? #5 __libc_start_main in "/lib/x86_64-linux-gnu/libc.so.6" #6 ? at ??:?

24 March 2021 0 0 View