Hi All:
I would like to request you all to let me know the information about any organizations or institutions which perform in-vivo anti-tubercular assay of synthetic compounds as a part of research work along with Animal Ethics Certificate...?
Do anyone know about Grindstone synthesis for the synthesis of organic molecules? Some of the researchers are not confident about the process and few are working only on grindstone synthesis as...
31 December 2018 260 3 View
While running a chemical reaction, one will use either TLC monitoring or Spectral analysis to confirm the completion of the reaction. Are there any other methods apart from TLC and spectral...
07 August 2018 1,253 2 View
I would like to request list of methods used to predict the size of binding cavity of an enzyme or a receptor.
06 July 2018 1,960 7 View
Is it possible to get yield of a chemical product more than 100%...? If so, how one can defend this situation? I am working on Condensation reactions using organic solvent free synthesis. For some...
05 June 2018 365 17 View
If any researcher worked on p-aminosalicylic acid and its derivatives, kindly let me know a simple method to convert p-aminosalicylic acid to its hydrazide form, i.e., 4-amino-2-hydroxybenzohydrazide.
04 May 2018 2,622 3 View
I am running a synthetic step to get Schiff's base today. Methyl-4-aminosalicylate and benzaldehyde (in 1:1 molar ratio) in presence of 2-3 drops of acetic acid and absolute ethanol as solvent...
04 May 2018 3,130 24 View
I would like to request the Researchers to let me know any procedures or references to carryout synthesis of Schiff bases of 4-Aminosalicylic acid when treated with different substituted...
02 March 2018 3,149 10 View
What happens when: 1. HMGCS2 Expression is enhanced....? 2. PfA-M1 aminopeptidase is inhibited....? 3. Mcl-1 is antagonised (inhibited).....? (All these have been estimated using in-silico...
11 December 2016 1,987 5 View
I had synthesized a compound having two side chains, each side chain is having a Schiff's base (>C=N-), so there will be chance of having 4 isomers. Which will be the best method to separate...
11 December 2016 6,328 5 View
How to prepare Benzophenone hydrazone by reacting benzophenone with 99% hydrazine hydrate? Methods are there preparation of Benzophenone hydrazone from benzophenone and anhydrous hydrazine and...
03 April 2015 1,369 9 View
Estemeed colleagues, I found some issues regarding the quantification of the data for TNBS assay. There are different protocols on how to perform that but it is clear to me the "fil rouge" that...
02 March 2021 2,616 1 View
I am a research scholar working on heavy metal stress on plants. I will be doing biochemical characterisation( protein, carbohydrate, proline, antioxidant enzymes and many more assays) at interval...
01 March 2021 6,999 3 View
Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...
01 March 2021 8,169 2 View
I am aiming to determine the ADC values of a commercial fish feed, but I do not have a steam pelleter or extruder available to me. Ideally, the pellets could be coated with some inert marker....
28 February 2021 7,967 3 View
When you use RIA, with a control the unknown sample with antibodies, you bare in mind the binding sites of the antibodies. However you still need to measure labelled antigen (radioactive) and not...
28 February 2021 2,133 3 View
The size of data generated by Ethovision is huge. Having NAS system for data storage seems to be a good option, I am wondering whether Ethovision can directly store the data to the NAS system...
27 February 2021 6,350 2 View
I have a time series data of some biochemical studies ( DNA and Chromosomal damage) which I intend to use to further predict into future without necessarily conducting the assay for an extended...
23 February 2021 7,842 1 View
The whole world is in a mess and paused. We all are tired of seeing hypermasculinized and destructive leaderships all around us. This world has seen enough of the aggressive patriarchal social...
23 February 2021 292 7 View
I would like to know what is the standard protocol in the number of worms per plate and number of plates per concentration of extract X in a lifespan assay done in solid media and not automated...
23 February 2021 9,933 1 View
New to the field of cell therapy. Why fluorescent-labeled antibodies to target cell antigens are not used for determining target cell count by flow cytometry in cytotoxicity assay (eg car-t)? Cell...
21 February 2021 3,278 3 View