Nagendra Babu Mennuru

13 Questions 19 Answers 0 Followers

Questions related from Nagendra Babu Mennuru

Are there any Organizations or Institutions performing in vivo anti-tubercular assay in India..?

Hi All: I would like to request you all to let me know the information about any organizations or institutions which perform in-vivo anti-tubercular assay of synthetic compounds as a part of...

01 January 2019 4,788 0 View

Can one depend on Grindstone Synthesis in Organic Synthesis...?

Do anyone know about Grindstone synthesis for the synthesis of organic molecules? Some of the researchers are not confident about the process and few are working only on grindstone synthesis as...

01 January 2019 336 3 View

Apart from monitoring TLC & Spectral analysis during the reaction, are there any other methods to determine completion of reaction..?

While running a chemical reaction, one will use either TLC monitoring or Spectral analysis to confirm the completion of the reaction. Are there any other methods apart from TLC and spectral...

08 August 2018 1,309 2 View

What are the methods to predict binding cavity size of an enzyme or receptor?

I would like to request list of methods used to predict the size of binding cavity of an enzyme or a receptor.

07 July 2018 1,999 7 View

Is it possible to get yield more than 100% in a chemical reaction....?

Is it possible to get yield of a chemical product more than 100%...? If so, how one can defend this situation? I am working on Condensation reactions using organic solvent free synthesis. For some...

06 June 2018 436 17 View

Why Methyl-4-aminosalicylate is not reacting with benzaldehyde....?

I am running a synthetic step to get Schiff's base today. Methyl-4-aminosalicylate and benzaldehyde (in 1:1 molar ratio) in presence of 2-3 drops of acetic acid and absolute ethanol as solvent...

05 May 2018 3,171 24 View

Do anyone worked on conversion of p-aminosalicylic acid to its hydrazide..?

If any researcher worked on p-aminosalicylic acid and its derivatives, kindly let me know a simple method to convert p-aminosalicylic acid to its hydrazide form, i.e., 4-amino-2-hydroxybenzohydrazide.

05 May 2018 2,690 3 View

Could any Researcher kindly let me know the simple and most atom efficient synthetic procedure for Schiff bases of p-Aminosalicylic acid?

I would like to request the Researchers to let me know any procedures or references to carryout synthesis of Schiff bases of 4-Aminosalicylic acid when treated with different substituted...

03 March 2018 3,194 10 View

What happens when the following events are noticed in Human Being?

What happens when: 1. HMGCS2 Expression is enhanced....? 2. PfA-M1 aminopeptidase is inhibited....? 3. Mcl-1 is antagonised (inhibited).....? (All these have been estimated using in-silico...

12 December 2016 2,022 5 View

How to separate E and Z isomers?

I had synthesized a compound having two side chains, each side chain is having a Schiff's base (>C=N-), so there will be chance of having 4 isomers. Which will be the best method to separate...

12 December 2016 6,370 5 View

How can I prepare Benzophenone hydrazone using 99% Hydrazine hydrate?

How to prepare Benzophenone hydrazone by reacting benzophenone with 99% hydrazine hydrate? Methods are there preparation of Benzophenone hydrazone from benzophenone and anhydrous hydrazine and...

04 April 2015 1,434 9 View

Can someone let me know about the best in silico and in vitro screening methods for anti-HIV activity?

Does anyone let me know about the methods to screen anti-HIV activity for new chemical compounds which are expected to act on HIV-1 reverse transcriptase. I require both in silico as well as in...

03 March 2015 2,897 3 View

How can I prevent or control the decomposition of acetophenone phenylhydrazone?

Acetophenone Phenylhydrazone was synthesized and obtained as good yellow crystals after re-crystallization from ethanol. The formed crystals on exposure to air (air drying at room temperature)...

03 March 2015 5,129 22 View