what are the invivo screening methods for anti TB drug?
This is a publication fot the in vivo animal model best of luc
I have used Schrödinger (Glide) for docking
13 July 2024 3,003 1 View
Hi, I have isolated exosomes from mouse epididymis using SEC in 300ul eluate (PBS) volume. I intend to concentrate the sample in order to increase the protein concentration (for LC-MS/MS) but I am...
29 August 2023 9,013 0 View
Hello I have a query regarding calculation of Projected DOS, using Quantum espresso (QE). We are studying about a oxide structure, and as it is spin polarized calculation we are using fully...
05 March 2023 8,180 0 View
Hello!!! I am a novice in quantum espresso, so I need your help in this regard. We are currently working on the 1x1x1 Ni3Mo (001) surface, to find out the change in the Gibb's free energy when...
25 January 2023 7,794 2 View
Hello !! I am a novice in Quantum Espresso. Please help me out in the following problem: We are trying to optimise Pt(111) surface , it is important to note that even though the attached files...
15 December 2022 6,786 5 View
Somebody kindly send template of World Journal of Engineering.
13 December 2022 4,752 4 View
I want to convert scale in a microscopy image 200x to micrometer scale
21 July 2022 9,730 1 View
We want to quantify an IHC image for specific expression of proinflammatory cytokines using image J or any other academic software
25 May 2022 7,265 1 View
Dear researchers, I wish to understand the role of grain growth inhibitor in controlling the microstructure of the ceramic pellet. How it controls the growth? Also, I wish to know the grain...
15 January 2021 4,196 3 View
Hi all, I wish to know about a common problem faced by most of the researchers who are dealing with ceramic materials that my ceramic powder is sticking with the balls after the operation. can...
02 December 2020 8,494 3 View
I am experimenting with cancer and non-cancer cells in a 12-well plate for 4 days with a seeding density 1*10^4/well, however, I noticed that the control group growth rate slows down on D3. Should...
07 August 2024 2,283 2 View
I work on MCF7 cell cell for anticaner purpose and I wa to do drug preperation the drug ( secondary metabolites extracted from Aspergillus) My question which solvent is better with these secodary...
03 August 2024 4,725 2 View
Hello, if you made a transwell assay where you incubate the cells with a nanoparticle-encapsulated drug and considering that in the oposite compartment you'll have both the free and encapsulte...
03 August 2024 2,730 1 View
I want to perform a CRISPRa/i library screening for candidate regulatory factors that affect pathogenic Th17 differentiation in PBMC. But I am wondering how to define the size of gene library, so...
31 July 2024 2,150 0 View
I have been running a MAGeCK test command on the terminal for a CRISPR screen to rank sgRNAs and genes based on the read count tables. However, I get only the plot of the top-ranked genes...
28 July 2024 9,811 1 View
if you have MRS broth already prepared, what is the manner you will follow for preparing hyper-sweet medium for screening of EPS producer LAB? what the concentration of saccharose or glucose you...
26 July 2024 6,606 0 View
I am working in the filed of long acting drugs with Nano formulation. I want to study the efficacy of my formulation in 2D cell cultures while this required media change on every two days. In such...
24 July 2024 8,696 0 View
Hello, I am searching for the binding position of a drug in a ribosome, based on previous work indicating it binds there. The resolution of the ribosome-drug Cryo-EM map is around 2.5 Å. I've been...
19 July 2024 2,155 0 View
I have conducted virtual screening using Schrödinger on a database of 17,000 molecules. Unfortunately, I cannot use the system with the Schrödinger license at the moment. I am trying to find a way...
18 July 2024 2,881 4 View
It was assumed that 4E8 T cells should be isolated and activated using plate-bound anti-human CD3, after which would be used for a genome-wide CRISPR screen. (Ref: Genome-wide CRISPR Screens in...
17 July 2024 3,371 0 View
