Control in microstructure with growth inhibitor?

Dear researchers, I wish to understand the role of grain growth inhibitor in controlling the microstructure of the ceramic pellet. How it controls the growth? Also, I wish to know the grain...

15 January 2021 3,859 3 View

Optimization technique in ball mill?

Hi all, I wish to know about a common problem faced by most of the researchers who are dealing with ceramic materials that my ceramic powder is sticking with the balls after the operation. can...

02 December 2020 8,232 3 View

Which one is best for extraction method MICROWAVE OR Soxhlet for leaf components?

I want to isolate components from leaf material, so I have beter solvets but suggest me method which will improve yield and purity

08 September 2020 1,003 2 View

What is the best method and solvent for isolation of alkaloids from leaves?

my target to isolate alkaloids from plant leaves, as phytochemistry of plant reported for some alkaloid derivatives , so please guide me.

01 August 2020 7,376 15 View

Are there any photonic resonating structures which show a blueshift in their spectral response upon increasing the refractive index of the top region?

This question is more in regard to the resonant structures used for sensing applications, namely surface plasmon resonance, photonic crystals and guided-mode resonance based devices, etc which all...

17 March 2020 6,800 3 View

How to run my model by using double precision executable in Abaqus?

I created a rolling model by using Abaqus/Explicit. All the warnings and errors, I corrected but still have a problem with one warning. The warning is about running the simulation in double...

25 March 2019 6,671 3 View

Does keeping tissue sample (patient biopsies) in Trizol for a long time (>6 month) degrades DNA ? or Leads to sheared DNA?

I am trying to isolate RNA and DNA from the tissue biopsy stored in Trizol at -80 degree for more than 6 months . I isolated RNA using the standard Trizol method and obtained good quality and...

22 November 2018 2,446 2 View

What is the difference between 2(-ddct) and fold change and relative expression?

I have calculated 2 (-ddct) for a set of 6 genes in 5 tissues using GAPDH as reference and one of the tissues as the calibrator. However, after computing the 2 (-ddct) values, which I believe is...

21 August 2018 3,108 3 View

I have extracted plant phenolics in aqueous methanol and want to prepare solution for gc-ms analysis to quantify phenolics. Help me in prep solution?

I want to quantify phenolics present in my aq. methanol extract using gc ms. But i want to make the extaract volatile so that it could separate out the phenolics. Please guide me to prepare my...

17 April 2018 6,145 4 View

How to increase viscosity of solvents like Acetone and IPA?

In one of formulation, I need to improve viscosity of Acetone ans IPA.How to increase viscosity of solvents like Acetone and IPA?

06 November 2017 2,195 2 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

How does an antibody have full intact antibody + half antibody?

Hello, I was just wondering how does a antibody have full intact antibody + half antibody? Is it because of the drug conjugation?

28 February 2021 1,577 1 View

How do I choose contrasts in SPM8?

I am learning how to use SPM for PET and PET-MR analysis, but I haven't found any great resources that explain how contrasts work. I have a series of PET images where our hypothesis argues that...

24 February 2021 1,534 2 View

Can I use a protein-devoid condition as my negative control in ELISA?

Hello, I am running a sandwich-type ELISA where I am trying to inhibit a protein-protein interaction using small molecules. For each experiment, I determine my Z' (Z-prime) to determine the...

23 February 2021 7,429 1 View

Does anyone have any ideas why drug-resistant malaria is increasing in Southeast Asia even when those drugs are no longer used?

When dealing with bacterial toxins, there are three varieties of microbes that develop in your petri dish: toxic, resistant, and susceptible. Initially, there are only toxic and vulnerable...

21 February 2021 6,084 5 View

What is the most prevalent drug related problem in the developed countries?

Detecting the drug related problems is an important step in the pharmaceutical care plan

21 February 2021 5,421 3 View

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19 February 2021 8,647 3 View

How to improve dissolution of neosome?

I have made neosome from herbal drug. Neosomes are stable. But I face problems in dissolution. I used minimum ratio of 1:1:0.25 ( Drug:span 60: Cholesterol and GMs. Now how can I active better...

17 February 2021 3,584 1 View

How can I import .sav file into LISREL?

I've just downloaded free trial version of LISREL 10.3 but I got stuck with importing .sav (IBM SPSS 25.) file. I mainly followed the steps of this video...

15 February 2021 752 2 View

How to determine the drug loading and the drug release capacity of a polymer micelle using UV spectroscopy?

Currently, I am working on PLA-PEG copolymer micelle for the drug delivery system. I have seen several papers where some researcher talks to centrifuge the drug-loaded micelle to separate the...

13 February 2021 5,822 7 View