What are the general challenges associated with functionalization of gold nanoparticles ?

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How gold procurement?

Please note it

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How gold procurement?

https://www.cleanteqwater.com/resources/case-studies/gold-mine-australia/

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Omar Gonzalez-Ortega

The biggest challenge is stability

Dmitriy Berillo

Stability of gold nano or other nano particles after or during surface modification with functional groups, or bio-recognition elements such as antibodies, DNA, aptamers or enzymes. Increase of temperature and /or ionic strength. pH change which will change the surface charge of gold nano nano particles it it was stabilized by electrolyte and therefore change of zeta potential, which in most cases leads to aggregation. In our work we studied AuNPs, PdNPs formation in situ chemically induced , thermally and light induced reduction of metal complexes. Article Cryogelation of Chitosan Using Noble-Metal Ions: In Situ For...

Article 3D-macroporous chitosan-based scaffolds with in situ formed ...

Yuri Mirgorod

New in the functionalization of gold nanoparticles is associated with their use in the diagnosis and treatment of human cancer. See for example

Article Gold Nanoparticles in Diagnostics and Therapeutics for Human Cancer

Sibasish Dutta

Thank you for your useful information.