It is not an equilibrium reaction

What parameters do you wish to know?

removing most of what??...the limiting reagent.

sorry about the previous reply and forget it. I just read the detailed of your problem. It always happen to us, especially for some reactions, if there are water or halogen hydride generated in situ, just remove or locked it timely. or maybe your conditions such as solvents are not the best, or sometimes you can have a try of microwave. I always just recycle the start materials if the product is enough for next. of course, if you focus on process study, you'd better solve it and good luck!

It is possible to use the non-limiting reactant as solvent ?

If water is formed, try to use a Dean-Stark system.

If you are using organomets coumpounds, the flask have to be completely dry (anhydrous)...

We need more data to answer...

It is a reaction between 2 solid reactants and 1 solid catalyst where i am using a solvent and heating it

What kind of reaction is it (nucleophilic substitution, coupling reaction...) ??? Try another solvent (most common used organic solvents, ionic liquids,...) and/or another catalyst

substitution reaction. I am using halogenated solvents which have high boiling point.

Since you said you use a catalyst, have you tried to increase the catalyst loading to maximize your turn over? At least in this particular scenario, it is likely that your catalyst is getting "consumed," which in turn affects the conversion.

I understand you are not in a position to divulge your chemistry, but maybe you could divulge a wee bit as people are clearly showing interest in helping you. I am afraid beating about the bush isn't going to help anyone's cause.

I think increasing the catalyst loading may help. I have to try that out

Also I will check continuing the reaction for a longer time

I still see the spot of catalyst on TLC

Hi, Peter

I would not be surprised if you disclose all intricate details of your current project in a conference or seminar .You would clearly see the game then.

@Arnab:

1) I am not sure if extending the reaction time as is would help your cause. If the reaction suffers because your catalyst no longer "performs," then maybe a higher catalyst loading is what you would need to look into.

2) Not trying to defend Peter or anyone, but like I had stated beating about the bush is not helpful. Yes, intricate details cannot be divulged, but one can surely do better than stating "solid reactants / catalysts."

I am saying this only because of the attention your question has garnered. No offense meant. Best wishes with your pursuit.