Arnab Biswas

6 Questions 33 Answers 0 Followers

Questions related from Arnab Biswas

Has anyone ever done a reaction of phenylacetic acid or its derivatives with Carbonyl diimidazole?

Recently I had done this reaction with a phenyl derivative of phenylacetic acid with CDI(1,1 Carbonyl diimidazole) but the reaction never seems to go to completion no matter how long one keeps it....

07 July 2018 291 8 View

Are there instances in the literature where a work on chiral methodology has been published without assignment of absolute configuration?

Does anyone have any idea as to how to search for such articles using Google Scholar or SciFinder?

12 December 2017 5,243 5 View

What are the possibilities of determining absolute configuration of a chiral organic molecule?

Recently I have been trying to determine the absolute configuration of a chiral molecule using crystallization methods.It is either difficult to get good crystals even by changing solvent systems...

11 November 2017 2,697 7 View

How to separate 2 spots in Column Chromatography?

I tried 2 separate 2 spots which are not so close in a 4cm long TLC plate but everytime it used to come together.I packed a long column in 230-400 Silica, took minimum amount of slurry and did...

10 October 2017 3,568 9 View

When running HPLC for a new chiral compound for the 1st time how does one zero in on a chiral column to separate the peaks?

When I run new samples I use the method of trial and error to get the perfect column to separate the 2 enantiomers of a compound(for racemic case).How does one narrow in on a range of columns...

01 January 2017 3,701 10 View

What are the different ways to consume the limiting reactant(by TLC examination) in an organic reaction?

I have encountered many organic reactions where I had taken 2 reactants in the molar ratio of 1:2, 1:1.5 etc but after a while TLC examination showed that the limiting reactant(which has been...

08 August 2016 7,825 14 View