Peptide shuttles formed by 2–4 amino acid residues that cross the BBB through passive diffusion are more attractive since they may minimize the loss of activity upon conjugation. For details see the attached Article Blood-brain barrier shuttle peptides: An emerging paradigm f...
Maurice Ekpenyong I want to design a peptide with about 8-9 amino acid. now i have an obstacle about cross it from blood brain barrier, because of it's molecular weight that must be 400-600 Da. Based on what you know, Can it cross?