What are the aims of designing new Alzheimer disease drugs despite there are existing drugs?

More Abduljelil Ajala's questions See All

Is it possible to directly measure analytes with ICP-MS in different matrixes?

Dear researchers, My research involves sequential extraction of sediments with different solvents (Acetic acid, Sodium acetate, Oxalic acid, and Ammonium oxalate monohydrate, Nitric acid) using...

19 November 2023 5,317 4 View

How to reduce the salinity of water samples before analyzing with ICP-MS?

Dear researchers, The salt intake for the ICP-MS we have is < 0.2%. I have river water sample with salinity ranged from 11.79 to 12.51 g/L. What do you think can be done so that these water...

15 November 2023 4,744 6 View

How can I join glass tubing with PEEK tubing?

I am working on creating a simple high pressure system but I need to make a connection between glass tubing and PEEK tubing.

17 May 2023 4,556 1 View

Is electrochemical reliable, precise and accurate method for quantification of heavy metals in environmental and biological samples?

Dear Researches, We have some biological and environmental samples to analyze for the concentrations of heavy and toxic metal(loid)s. The ICP-MS intended to be used is out of order for now. Is...

01 March 2023 5,392 4 View

What are the main reasons for structure base drug design, docking and pharmacokinetics of inhibitors against Alzheimer Disease?

i will appreciate your positive contributions.

05 December 2022 1,118 0 View

Is the information on nature of chemical bonds formed XRF possible?

Dear researchers, Is it possible to obtain information on the nature of the chemical bonds formed by an element when X-ray Fluorescence Spectrometry is used for analysis? If yes, How? Thanks for...

18 December 2021 4,122 5 View

How to separate essential oil from water in the distillate?

Hydrodistllation was used to erxtract essential oil from a natural product. What are the possible simple laboratory methods to isolate the essential oil from the distillate without loosing the...

18 December 2021 6,333 6 View

What is the simplest way to interpret FTIR spectrum?

Whenever there are slight differences in absorption bands of materials, it becomes confusing to distinguish them for me. Can someone help out with this? Thanks. Dr Tolulope O. Ajala.

04 July 2021 1,074 4 View

Trace metal speciation?

I am carrying out a research to assess the ecological risk associated with the speciation of trace and toxic metals in floodplain suspension. Bearing in mind that the reducible, oxidizable and...

18 August 2020 4,533 4 View

In my DSC Isothermal tests, Avrami coefficient is (n > 4).What is the significance to this n to the growth type of the polymer?

I am not sure if I may be doing something wrong but my R-squared for primary crystallization (Xt of 3% to 20%) is about 0.9998. I am also looking to compare my data/results. Working with PLA at...

22 January 2019 10,022 5 View

Is changing the medium during the experiment overestimate the results?

I am experimenting with cancer and non-cancer cells in a 12-well plate for 4 days with a seeding density 1*10^4/well, however, I noticed that the control group growth rate slows down on D3. Should...

07 August 2024 2,283 2 View

Is an invitation to join the editorial board of Clinical Cardiology Updates a scam?

I received an e-mail invitation to join the editorial board of Clinical Cardiology Updates. While I have published a few articles related to cardiovascular disease, there are lots of colleagues...

06 August 2024 8,981 8 View

In the situation below, can I apply braun and Clark thematic analysis?

I have a theoretical framework for preparing a interview guide to assess the unmet care needs of a sub population of chronically ill patients and their caregivers(dyadic interviews).

04 August 2024 8,798 7 View

Which solvent is better to dissolve with secondary metabolites extracted from fungi?

I work on MCF7 cell cell for anticaner purpose and I wa to do drug preperation the drug ( secondary metabolites extracted from Aspergillus) My question which solvent is better with these secodary...

03 August 2024 4,725 2 View

Can i quantify a nanoparticle encapsulated in cell culture medium by hplc?

Hello, if you made a transwell assay where you incubate the cells with a nanoparticle-encapsulated drug and considering that in the oposite compartment you'll have both the free and encapsulte...

03 August 2024 2,730 1 View

How are aPTT and PT values reduced after hemodialysis compared to before dialysis value in patients with chronic kidney disease?

I am conducting my research regarding blood coagulation in patients with CKD. I observed a reduction in post hemodialysis aPTT and PT values compared to pre hemodialysis values. But most of...

30 July 2024 3,467 0 View

How to maintain the drug concentration in cell culture study for long term?

I am working in the filed of long acting drugs with Nano formulation. I want to study the efficacy of my formulation in 2D cell cultures while this required media change on every two days. In such...

24 July 2024 8,696 0 View

Could someone please provide a list of journals that accept the application of methodologies in nature-based solutions?

I am looking for journals that admit the publication of results from applying the IUCN Standard for designing and monitoring Nature-based solutions. Many thanks for considering my request.

23 July 2024 6,444 2 View

What role does the gut microbiome play in immune system modulation and disease susceptibility?

Only Probiotics Related

22 July 2024 6,454 0 View

How can I determine if a drug binds to a ribosome using a Cryo-EM map?

Hello, I am searching for the binding position of a drug in a ribosome, based on previous work indicating it binds there. The resolution of the ribosome-drug Cryo-EM map is around 2.5 Å. I've been...

19 July 2024 2,155 0 View

Nilo Arturo Ramos Rojas

El último Fármaco sacado al mercado aparentemente tiene efecto para detener el deterioro mental del paciente

Primero conocer la enfermedad y los anteriores medicamentos que existian para esta enfermedad y luego entrar en lo último que hay en el mercado. eso te lleva como 45 minutos .