In some papers they say dynamic SPECT provides a better contrast between normal and decreased flow regions than can be obtained from static imaging. what are the other advantages,if any?
Do you mean gated cardiac SPECT imaging, rather than true dynamic imaging? If the data is gated, this counteract some of the blurring encountered from the beating of the heart. Obviously if this is not gated the beating causes more "smearing" of the counts, meaning that the contrast is reduced, but this is still the only acquisition method for kinetic modeling. It also depends on the type of camera, i.e. a standard sodium-iodide camera probably cannot perform true dynamic imaging because of the rotation time, but there is plenty research out there on dynamic imaging using solid state systems
Non-gated (static) will be blurred due to movements of the Heart (cardiac cycle). In gated SPECT you evaluate on end-diastolic images that are non-blurred making detection of defects easier. On the negative site you have poorer count-statistics since you only use information from part of the cardiac cycle.
Dynamic (gated) SPECT also allows for estimation of LVEF, LVEDV, LVESV and LVSV.
Dynamic SPECT, is a list mode SPECT acquisition developed for new semiconductor gammacameras, who permit a continuos acquisition over cardiac region without camera moving. In this case, the reconstruction of cardiac slices gain more contrast vs standard reconstruction,
The information provided by gated SPECT regarding LV wall motion and LV function adss powreful adjunctive data to myocardial perfusion imaging particulary in assesment of myocardial viability, assesment risk of patioents with known CAD, distinguishing ischemic from nonischemic cardiomyopathy and identification of suspected attenuation artifacts.
Well, in recents papers (such as Glenn Wells et al. 10.2967/jnumed.114.139782) the potential of fast cardiac SPECT cameras to acquire in a dynamic way to "track" the delivery and uptake of perfusion agents is investigated (i.e. the tracer is injected while the patient is sitting/lying in/under the camera). Based on such data, quantification of absolute myocardial blood flow similar to PET would be possible. Theoretically this allows - amongst others advantages - the detection of balanced three vessel disease as the stress flow is reduced in absolute terms (ml/min/gram) but the (static) images look almost normal. The problem, however, is that conventional SPECT tracers are much less extracted by the myocardium as typical PET agents - thus this quantification is much less reliable.
Linear high-extraction tracers like 99mTc-teboroxime used with solid state systems are allowing more accurate quantitation, and these "old" tracers are making a comeback because the tracer kinetics were too fast for older imaging systems (See a recent study by Okada et al, EJNMMI Res, 4,42, 2014). Clearly exciting times ahead for MPI SPECT.
el spect dinamico aporta datos funcionales (contractilidad global y segmentaria, fevi, engrosamiento miocardico, estudios de fase es decir sincronismo, ect), lo que lo hace superior al spect estatico.
by saying "dynamic SPECT" I didn't mean "gated SPECT". of course maybe sometimes gated SPECT can be considered as a kind of dynamic SPECT. what I am trying to say is the concept of measuring kinetic parameters of heart.
The advantage of cardiac dynamic SPECT imaging over conventional SPECT imaging is that cardiac dynamic SPECT imaging allow to estimate the absolute kinetic parameters of left ventricle.
Dynamic SPECT didn't mean "gated SPECT". In dynamic SPECT the data are collected in time of dose administration.