It's well established that the V617F mutation (c.1849G>T) is located in exon 14 of the JAK2 gene. However, when attempting to locate this mutation using the CCDS (Consensus Coding Sequence) file from NCBI for the reference sequence NM_004972.3, the nucleotide position 1849 appears to be in exon 12 instead of exon 14. This discrepancy is confusing, and I am unsure what the underlying issue might be.