I have RNAseq data from some human WT and KO macrophages. I have a list of DEGs from this comparison.

However in addition I have been asked to demonstrate using the data I have that they (both WT and KO) are more like macrophages than other PBMC and then also secondly to compare them to other macrophage subsets.

I have searched the GEO databases and there are datasets available that compare many human PBMC and I am sure I can also find some comparing macrophage subsets however how do I practically then compare may data with these datasets to demonstrate this?

Any help very much appreciated