To find an ideal solvent for electrospinning of carboxymethyl chitosan I searched through many articles but most of them included addition of some polymers such as PVA or PEO to the solution (except one by Sohofi et. al 2014). I tried dissolving carboxymethyl chitosan into aqueous solutions including acetic acid, Dimethyl Formamide, DMSO etc. but as a result only droplet spray and arc formation is observed, I'm unable to establish a stable taylor cone jet or nanofibres. Please provide me insights for electrospinning of only Carboxymethyl chitosan without any polymeric addition.
To electrospin carboxymethyl chitosan (CMCS) without adding other polymers, consider using trifluoroacetic acid (TFA) or concentrated acetic acid as solvents. Optimize the concentration of CMCS and fine-tune electrospinning parameters such as voltage, flow rate, and collector distance. Ensure solution homogeneity and experiment with needle diameter and collector materials to achieve stable nanofiber formation.
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