Has anyone else investigated the PTP1B inhibitor trodusquemine (TD) and its potential to reverse atherosclerosis? A mouse study showed that a single exposure of TD reversed atherosclerosis.
TD has been shown to be safe for humans.
It has been studied in addressing Type II diabetes with a successful result. A breast cancer study was in process but the sponsor went belly-up financially, terminating the study.
TD, by the way, is responsible for salamanders, dogfish sharks and other animals being able to re-generated an entire limb.