Thiazole orange displacement method for G-Quadruplex is valid way to evaluate compounds or not?

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Please suggest most appropriate PDB ID for MD simulations for cMYC G-Quadruplex stabilizing ligands?

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MD simulations for G-Quadruplex stabilizing agents?

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Josué Carvalho

Dear Vijay,

We have recently published a paper using this method to evaluate the binding ability of G4 ligands. The results were crosschecked by other techniques and we're valid. As long as you correlate the results with additional techniques, I don't see why it should not be used.

Josué

Vijay Nimbarte

Dear Josué Carvalho ,

Thank you so much for your opinion ....I am following your work now...

Greetings,

Vijay