How can I download germline variants info from TCGA?

I have access to controlled data. I have done this some years ago, but can't seem to figure out the new interface. Ideas?

09 October 2016 6,677 3 View

What do you think about the Lancet letter regarding Gaza?

Below is a letter I have sent to Elsevier, the publisher behind Lancer: To Mr. Reller, Vice President for Global Corporate Relations at Elsevier I share the feelings expressed in the letter sent...

09 October 2014 5,648 1 View

The cost of starting a new on-line journal?

I am trying to start a new journal. I hope to make it free-open access if I can raise funds for that. Does anyone have any idea how much that should cost? What's the minimal stuff? 1 full timer?...

07 August 2014 4,835 0 View

Is anyone working on Personalized (precision) cancer medicine?

We are working on a new wiki for precision cancer medicine. If you are working in the field, please let me know what you think (registration is required): http://rubinlab.bgu.ac.il/pcm/

07 August 2013 584 2 View

Is anyone familiar with running weka with a sun grid engine?

I am trying to use weka on our cluster, running sun grid engine. I installed Weka myself without root permission, and added CLASSPATH info to .rcsh. When I run a shell command invoking WEKA (with...

07 August 2013 2,221 4 View

Is my SNP on some commercial platform?

Does anybody know how to check if a new SNP is on ANY chip? I am looking for experiments in which a specfific SNP has been evaluated.

10 November 2012 894 4 View

How to align short reads to repetitive regions?

I am trying to align NGS data to repetitive regions. Straight-forward use of tools such as BWA fails. Any suggestions?

08 September 2012 1,295 6 View

Why are some nodes in Mega5 NJ tree shown without boostrap values?

My students noticed that you occasionally get no bootstrap values in a Mega5 tree. Bug? filtering? Any ideas? I attach the FASTA of the sequences used to generate the tree. Eitan

05 June 2012 9,291 15 View

How to compare the quality of clustering solution for the same dataset?

I always wondered how to test for the significance of clustering results. Now I have an urgent need. I want to show that when my input is organized in a biologically meaningful way. For that, I...

05 June 2012 2,977 15 View

Did anyone test the new compression tools for BAM format?

We have developed our own tool for compression, which saves ~70% while creating "regular" BAM files. But we are seeing all these new formats that are space economic - but I want to hear from...

04 May 2012 5,974 1 View

How to compare two groups with only two measurements?

Hiiiii everyone! I have an enquiry on statistical analysis. I was looking for many forum and it's still cannot solve my problem. I want to compare means of two groups of data but only with two...

03 March 2021 8,796 3 View

Enhanced Yellow Fluorescent Protein (Aequorea victoria) DNA sequence?

I am on the lookout for the Enhanced Yellow Fluorescent Protein (Aequorea victoria) DNA sequence. Does anyone know where I can find it? Thank you in advance

03 March 2021 3,568 1 View

What kind of fluid could I use for a pitfall trap that also does not invalidate molecular testing?

Hi, I want to start testing pitfall trap to obtain ants samples, but I need to conduct molecular analysis on those insects. So, what kind of fluid can I use? Ethanol expires too early and I need...

03 March 2021 5,978 5 View

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10?

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10? Since, the growth curve from day 2 to 10 won't be like the "Logistic curve" it might not follow logistic...

03 March 2021 1,401 3 View

Do we need to write protocol for a second study of a systematic review that has been registered and published?

I have conducted and published a systematic review and meta-analysis research with the topic related to public health and health pomotion (protocol was registed in PROSPERO). Now we want to...

03 March 2021 8,920 3 View

How to increase a model accuracy ?

dear community, my model is based feature extraction from non stationary signals using discrete Wavelet Transform and then using statistical features then machine learning classifiers in order to...

03 March 2021 6,994 5 View

Do I need to do linear regression before running mediation analysis using PROCESS MACRO by Hayes ?

I just wanted to check if I need to run a linear regression separately if I am using PROCESS MACRO to run mediation analysis. Thank you.

02 March 2021 4,359 3 View

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02 March 2021 932 1 View

Sample dilution for quantitative analysis using ELISA?

If the detection range is in ng/ml but the reference range is in ug/ml for a molecule or protein in serum or plasma .how to dilute and what is the initial volume to be taken for quantitative analysis

02 March 2021 7,670 3 View

Is There Any Feasible Method To Test Fluorescent Compounds Other Than Fluorescence Spectrometers ??

Is There Any Feasible Method To Test The Efficiency Of Fluorescent Compounds Other Than UV Spectrometers ? Suggestions Would Be Appreciated !

02 March 2021 5,785 3 View