Greetings!
Respected experts!
I want to load drug on nanopaeticles.
I have resuspended my nanopaeticles in distilled water, then I have dissolved my drug in 98% ethanol .Then I mixed nanoparticle resuspension and drug solution and maintained PH 10.5.and did Magnetic stirrer for 24 hours. Is my procedure of drug loading correct? I have used 2 different solvents , can we use two different solvents in this way?
Thanks
Your queistion is very general.
It depends on many factors.
I just surperised, 24 h for solving drug?
If you have ultrasonic water bath or ultrasonic probe sonicator, therefore, you will not need to use any solvent other than water.
Thorough mixing or homogenization of your drug and mechanical dispersion or aq. colloidal solution of nanoparticles using sonication bath for 15-20 minutes at least.
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