On many occasions abnormalities of thyroid hormones are present in cases of urticaria. Is the treatment of urticaria independent of thyroid hormonal abnormalities?
No, it is probably related in a subset of patients as treatment of the underlying thyroid disorder in this subset of patients leads to a significant reduction in the severity of urticaria as well as antihistaminc dependence.
The percentage of patients with chronic urticaria who have antithyroglobulin antibody, antimicrosomal antibody, or both is 27 percent, and 19 percent have abnormal thyroid function. The thyroid abnormality appears to be a parallel abnormality and may
reflect the presence of an underlying autoimmune process.Treatment of underlying thyroid disorder should be considered. Levothyroxine has been proposed in patients with antithyroid anti-bodies, even if the patient is euthyroid. Such treatment, however, carries a risk of inducing hyperthyroidism, and its efficacy has not been proved.