Most of papers and review articles, that I have come across, only talks about abnormally elevated level of lactate in moderate or severe TBI. I could not find any such report in case of mild TBI.
i) Could someone please provide me some reference/s where elevated level of lactate has been reported in case of mild TBI?
ii) We know that neurophysiological and neurological dysfunction resolves with in few days/weeks in most of patients. However, a significant portion of patients with mild TBI (~15%) report persistent cognitive dysfunction weeks, months and years post injury. Could some TBI expert be kind enough to share his/her insight into metabolic imbalance expected in those patients with poor recovery?
Regards,
Dushyant