Is there any interaction equivalent of Cochran's Q test (like 2x3 design)?

I have data on the effectiveness of the three treatments: T1, T2 and T3 for each patient. Each variable is coded dichotomously - 0 = drug not working; 1 = drug is working. The patient could feel...

30 November 2020 1,146 14 View

Two pair of peaks of quinone/hydroquinone redox probe on GCe?

Hello, I recently stumbled upon a voltammogram of HQ/Q in 0.1M NaCl on glassy carbon electrode. I was surprised to see two pairs of peaks present on the graph. As far as I know it is a two...

29 June 2020 1,833 2 View

Non-equal variances t-test in SPSS - it's Welch or Cochran-Cox?

Can anyone help me answer the question of whether t test for unequal variances is calculated in SPSS according to Welch or Cochran-Cox correction? Test statistics are the same, they differ only...

29 May 2019 7,445 14 View

Is there any reason why one can not reduce dimensions with PCA/Alpha before putting them into SEM model?

Suppose I have three measurable variables (A, B, C on figure below) and one latent (L) in my SEM model. This one latent one is a construct/dimension consisting of 5 questions from some...

07 April 2019 905 6 View

What is precipitated in buffer solution stored in glass bottle?

Does anyone know what is precipitated in carbonate buffer solution stored in typical amber glass bottle (picture is an attachment)? The carbonate buffer in the bottle is Na2CO3/NaHCO3, pH=10.0...

06 February 2019 7,556 3 View

How many animals are required for experiment?

I want to compare 4 different methods of bladder cancer induction and I have to calculate sample size. How many animals I have to used to get appropriate statistical power?

25 November 2018 151 2 View

How to generate average contact maps from molecular dynamics?

Hi, I am looking for a way to generate a contact map between each residue of a protein during MD simulations. I.e. for each pair of residues, count the number of frames during which they form...

05 May 2018 2,023 8 View

How to get rid of a primer smear in pcr (negative control problem)?

Hello everyone My pcr was doing just fine for few months till about 3 weeks ago I started to get smears in all my samples and positive and negative controls as well. I'm preparing my reaction...

21 March 2018 2,405 7 View

How can I cryopreservate Human Hepatic Stellate Cells?

Dear all, Does anyone know or have an experience in freezing (cryopreservation) of the primary Human Hepatic Stellate Cells? How much DMSO is recommended to use? I read that cryopreservation of...

03 March 2018 9,712 2 View

Freezing atoms in gaussian - how to do it?

Hello, I'm working on a structure with about 200 atoms. It is important for me to freeze a significant part of it for the time of optimization so that the arrangement of the given atoms with each...

05 February 2018 649 7 View

Do we need to write protocol for a second study of a systematic review that has been registered and published?

I have conducted and published a systematic review and meta-analysis research with the topic related to public health and health pomotion (protocol was registed in PROSPERO). Now we want to...

03 March 2021 8,920 3 View

No title

Hi, I have several doubts about one paper (Systematic Literature Review) that was rejected. The main topic is Single-Board Computers in engineering education during the period 2010-2020. The...

01 March 2021 9,015 3 View

Which software is better to write systematic review paper?

We have seen some authors use some software to write review paper. As obvious, the study of all published papers concerning our studying field is not possible and these software can help us to...

27 February 2021 6,296 1 View

How to determine implicit ontological and epistemological stance?

I am hoping for some guidance and additional reading material that will assist me in determining ontological and epistemological stance when not explicitly detailed within the research. Here is...

26 February 2021 227 5 View

Centrality measures computation in Biblioshiny/ Vosviewer?

26 February 2021 7,279 2 View

When to use different framework?

Hi, can I use both conceptual framework and theoretical framework in my systematic review? My future study plan is to use a theory. In this situation for my systematic review should I use both or...

18 February 2021 9,581 2 View

Do you know any reporting tool, guidelines for credibility assessment tool used for studies/publications with Artificial Intelligence?

I want to conduct a Systematic Review and assess the quality of methods used/proposed by researchers. I found out that scientists often utilize QUADAS for that...

05 February 2021 8,743 5 View

How to best engender critical thinking in K-12 education?

From my observations, there appear to be three principal avenues to engender critical thinking in education K-12: debate; mathematics, and science. For some students, all three avenues are...

04 February 2021 9,605 7 View

What will be the possible analysis plan for descriptive outcome?

Hi everyone I am busy with a Systematic review. Unfortunately, my protocol has been returned back because of my analysis plan that will not answer my question. Can you please advise on the...

02 February 2021 6,190 2 View

How can a traditional medicine exist if its validated outcome is translated into molecular mechanism for acceptance of modern medicine?

A traditional medicine (e.g. Unani System of Medicine) has its own philosophy of treatment of a disease. Nowadays, there is emerging demand to validate the effectiveness of an intervention (a...

05 January 2021 9,472 5 View