We work a lot with an enda+/endonuclease+ strain of ecoli (stbl3), so for minipreps we just do the PB wash step and things work fine.
However, we sometimes have trouble with low quality DNA from maxipreps using the Qiagen kit.
I couldn't find this anywhere: Do Qiagen maxi kits tolerate endA+ ecoli strains? I read some other maxi kits have no trouble with endA+ strains, but I couldn't find anything about Qiagen's maxi kit.
I'd like to just switch to another ecoli strain, but my professor doesn't believe anything without extremely definitive evidence.
You can try to add the PB wash step to the maxi-prep although it is not part of the standard protocol (just add it after passing the lysate's supernatant in the column) and that should probably solve the endA issues. As for other kit, I used the maxi prep from thermo which worked fine and is cheaper than the qiagen kits (the step to handle endA+ strain is integrated as part of the standard protocol).
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