As i have to do selective esterification of glutamic acid which contain 2 carboxylic group so i need to protect one group so which reagent i can use for protection
Firstly convert the amino acid into its diester salt form by well known procedures, then hydrolyse the salt by aqueous copper sulfate and filter the copper complex of monoester. Further decompose the complex with EDTA aq solution at reflux , cool to get the desired gamma monoester.