Hello all. We are trying to get access to prostate cancer cell lines that were derived from patients who were Black or of African descent. There are numerous relevant cell lines reported in the literature, but they are hard to find for purchase - the only one we have found for sale is MDA PCa 2b / CRL-2422. Would anyone be able to provide a link to any others that are for purchase, or else be willing to share a flask or vial with us if you have some in your lab? We have reached out to some authors who developed relevant cell lines, but unfortunately haven't heard back yet.
Many thanks!
Dear Dr. Susan Heavey
RC-77T/E is a prostate cancer cell line developed from an African American prostate cancer patient. You may want to refer to the paper attached below.
Article Establishment and characterization of a pair of non-malignan...
Have you been able to contact Dr. Clayton C. Yates, Ph.D.
Department of Biology and Center for Cancer Research Tuskegee University, Tuskegee AL 36088.
Office (334) 727-8949 or Email: [email protected]
Tuskegee University’s Clayton Yates’ lab is one of several groups working to increase the number of African American cell line models. His lab recently developed this African American prostate cancer cell line, RC-77T/E, but whether it is commercially available I would not know.
Regards,
Malcolm Nobre
Thank you very much! Yes, this is on our list (shared below) but unfortunately the only cell line out of these that we've been able to find available for purchase is MDA-PCa-2b. Do you know where we can get access to any others, by any chance?
Thanks very much for the extra info and for the contact info, I'll reach out now as this seems like a great place to look!
- MDA-PCa-2a
- MDA-PCa-2b
- P69SV40T
- RC-77T/E
- AA-103B
- iHGPINc
- S006AA
- E006AA
Dear Dr. Susan Heavey
From the list of cell lines provided, I would like to pass on some information about E006AA cell line. A study has shown that E006AA cell line classified as African American actually carries more than 90% European ancestry.
Many published research papers have used either E006AA or E006AA-hT cells, including several of which used this cell line specifically to investigate the biology of prostate cancer in African American men.
For more information you may want to refer to the link provided below.
https://cen.acs.org/biological-chemistry/cancer/Genetic-tests-reveal-cancer-cell/97/i10
Best.
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