When you prescribe a medication, what is your go-to-site/book/reference to check for adverse reactions? And what type of adverse reactions do you check? Is it type A adverse reactions only that you check?
And in other words: what are the most important adverse reactions that you must check?
Several:
1. Package insert
2. Physician Desk Reference
3. Online resources of FDA
4. Review published peer-reviewed journal articles
Dear Mostafa,
I would says that depends on the drug prescribed. Some have prevalent adverse effect and I specially have a look to them (asking the patients, blood samples...), but all type of adverse event have to be cued.
Didi you have a specific drug in mind ?
In France, we can saw references in package insert, Vidal ressource... and we can ask to the regional pharmacovigilance center or ANSM (National Security Agency of Health Products).
Dr.Dennis, do you mean by Physician desk reference the PDR.net website? Also why the package insert is the one that you check? Is it because it carries the most important information? And which peer reviewed articles you check? And when do you check?
Dennis Mazur
Dr. Emmanuelle , for example if the drug in Q is clindamycin, how would you go with regard to research? Which reference will you check first?
Emmanuelle Cugy
Dear Mostafa,
I will first do with my acquired knowledge, clindamycin is an antibiotic, near to macrolid, so it will have digestive disorders or allergy, and I think cardiac rythmic disorders.
Next, I check the package insert or Vidal source (or our national database http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=64829519). Here, I found that skin disorders is also frequent.
If the adverse effect is not easily found, I have a look on medical bibliography trought search engine. for example : https://www.ncbi.nlm.nih.gov/pubmed?term=%22Clindamycin%2Fadverse+effects%22%5BMesh%5D
hoping to have answered your question
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