I'm doing ADMET analysis in SwissADME and I have a problem understanding and identifying what should be the ideal classification: if a drug should be a P-glycoprotein substrate or not. Can you help me?
Hi. I am doing an agarose gel electrophoresis. After running PCR samples in a 2% agarose gel at 90V x 45' I obtained the results in the image. The ladder bands are not properly stained. For...
14 January 2021 2,316 4 View
Hello, I am currently analyzing properties of some minerals such as Bi2O3 by MD using Materials Studio, I need to obtain the cohesive energy density (CED) to obtain the solubility parameter,...
02 November 2020 4,356 1 View
I'm starting working on generating web apps UIs automatically applying machine learning methods. I recently read about pix2code and code2pix, which are in the line of what I want to do. Do any of...
30 August 2020 567 2 View
Dear peers, It would be much appreciated if you could suggest papers or reports that emphasize the sampling considerations for microplastics in soil/terrestrial/agricultural environments. Thanks!
27 August 2020 8,710 5 View
Dear researchers, I would much appreciate if you could explain or suggest good research papers regarding the effects of ocean acidification on the chemical composition of the valves of mainly...
31 December 2019 7,776 3 View
I'm researching microplastic abundance and distribution in sandy beaches. I compared microplastic abundance between the intertidal and supralittoral zones and also between 4 beaches. My data is...
07 November 2019 8,408 3 View
Ethanol can act as promotion enhancer and glycerin as well, when administered as co-solvents of BCS class III drugs. However, at the same concentration both excipients will have the same effect...
10 November 2017 4,798 1 View
I have read some responses on here about them looking at different things etc which I understand, but I'm more interested in asking how it should be reported following a significant ANOVA?
28 August 2016 8,280 2 View
It turns out to be very tedious form groups of subjects which are comparable on a set of variables, and not on other variables. It would be desirable and useful if there is any tool that can...
18 January 2016 9,858 4 View
How to calculate IC50 values to drugs that does not reach a 100% of inhibitory activity, for example? If I find a experimental value of 45% inhibition in the maximal concentration of solubility...
26 May 2015 5,707 3 View
What Characteristics makes CNN work better?
03 March 2021 1,458 4 View
How to manually calculate p value in ANOVA? what is the equation or formula for it?
03 March 2021 4,928 5 View
i am try to classify the x-ray images. During classification , can i block unwanted images (except x-ray image).
03 March 2021 7,100 1 View
The range of forms and sizes of cavities in rock is very big. Is there a classification scheme for rock cavities regarding their size and shape?
02 March 2021 4,511 3 View
Do you have some recommendations approaches on Image processing and classification of plant diseases using TensorFlow/Keras?
02 March 2021 1,493 4 View
I want to differentiate between normal and abnormal movement. For this reason, I am looking forward to this type of dataset.
01 March 2021 9,485 1 View
Pls share your thoughts
01 March 2021 7,330 4 View
I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...
01 March 2021 3,703 3 View
Hello, I was just wondering how does a antibody have full intact antibody + half antibody? Is it because of the drug conjugation?
28 February 2021 1,577 1 View
I am learning how to use SPM for PET and PET-MR analysis, but I haven't found any great resources that explain how contrasts work. I have a series of PET images where our hypothesis argues that...
24 February 2021 1,534 2 View