I'm doing ADMET analysis in SwissADME and I have a problem understanding and identifying what should be the ideal classification: if a drug should be a P-glycoprotein substrate or not. Can you help me?
"The Correlation between Nutrition and Transport Mechanism under Abiotic Stress in Plants: A Comprehensive Review" by Muhammad Saleem, Jianhua Zhang, Muhammad Qasim, Rashid Iqbal, and Li Song,...
23 July 2024 9,109 0 View
I've been working with activated sludge samples and have encountered a challenge in identifying certain structures/organisms that appear abundantly within the flocs during optical microscopy...
23 June 2024 9,584 1 View
Me gustaría saber qué usos tiene la base y para que ha sifdo utilizada https://www.chemnetbase.com/
04 June 2024 1,112 1 View
It is difficult, or even impossible, to find real performance metrics (transactions cost, time to transaction finality, transactions per second, etc.) on the different blockchains. In their...
13 May 2024 10,182 3 View
It is about my research using a orange peel pectin derived agar in cultivating bacteria that is very versatile and can grow on wide variety of conditions, can you suggest me a gram positive...
09 May 2024 7,376 0 View
Hi guys, I have prepared the small Mn3O4 NPs via the method reported in the literature. Details of the synthesis are as follows: 300 mg Mn(acac)2 and 9.63 ml oleylamine were heated at 150 ℃ for 9...
28 March 2024 3,838 2 View
The flow on macrophages Raw264.7 was conducted. Different from the previous result, the value of SSC-A and FSC-A have increased. Why are SSC-A and FSC-A increased on the flow results of Raw...
23 March 2024 3,333 4 View
En la asignatura de psicología del desarrollo, del segundo año de la carrera de Trabajo Social hice junto a otras dos compañeras un trabajo en la que a partir de una película o serie debíamos de...
04 March 2024 9,929 1 View
Hice un trabajo en la asignatura de Trabajo Social Individual y Familiar, en el segundo curso de la carrera de Trabajo Social en el que hablábamos sobre la modificación de la conductas en...
04 March 2024 6,601 1 View
I am looking for study participants who are instructional designers, business faculty, and business experts.
13 February 2024 5,785 2 View
I am experimenting with cancer and non-cancer cells in a 12-well plate for 4 days with a seeding density 1*10^4/well, however, I noticed that the control group growth rate slows down on D3. Should...
07 August 2024 2,283 2 View
I work on MCF7 cell cell for anticaner purpose and I wa to do drug preperation the drug ( secondary metabolites extracted from Aspergillus) My question which solvent is better with these secodary...
03 August 2024 4,725 2 View
Hello, if you made a transwell assay where you incubate the cells with a nanoparticle-encapsulated drug and considering that in the oposite compartment you'll have both the free and encapsulte...
03 August 2024 2,730 1 View
I have an RNA-seq data that I have analysed using Limma-voom and have extracted the gene IDs, log2FC and the p-values. At p value < 0.05, I have over 10,000 DEGs, however, when I run the GO...
31 July 2024 225 2 View
Dear All, My lab primarily works on insect wing patterns. In one of the projects, my student and I have defined 19 abnormality characters on the forewing and 6 abnormality characters on the...
31 July 2024 6,464 5 View
I have two groups that I test on three different tasks. I have 4 independent t-test, 6 paired t-test and 2 ANCOVA. My concern for which t-test should I conduct bonferroni correction. At the moment...
28 July 2024 7,827 6 View
I am working in the filed of long acting drugs with Nano formulation. I want to study the efficacy of my formulation in 2D cell cultures while this required media change on every two days. In such...
24 July 2024 8,696 0 View
Hello, I am searching for the binding position of a drug in a ribosome, based on previous work indicating it binds there. The resolution of the ribosome-drug Cryo-EM map is around 2.5 Å. I've been...
19 July 2024 2,155 0 View
Hello, when calculating the p value for the alleles in the table, how do we place the values in the chi-square test in the four-eyed table? Thank you very much for your attention.
17 July 2024 998 2 View
How to calculate percentage cumulative drug release when, Total volume of dissolution media = 250ml Added formulation was equivalent to 10mg of drug Sample withdrawn = 1ml each time Sink condition...
15 July 2024 4,192 1 View