Glutathione (GSH) serves as an important anti-oxidant in the brain by scavenging harmful reactive oxygen species that are generated during different molecular processes. The GSH level in the brain provides indirect information on oxidative stress of the brain
Glutamine synthetase (GS) activity, protein tyrosine nitration, and RNA oxidation,
Dear Dr. Al-Baghdadi, there are some relevant biomarkers of oxidative stress in brain, including antioxidant enzymes activity/expression (superoxide dismutase, catalase); and oxidative damage biomarkers such as malondialdehyde, hydroperoxides, carbonyl groups, etc.
Yes, Various antioxidant enzymes such as Superoxide dismutase (SOD), Catalase (CAT), Glutathione (GSH) and oxidative damage biomarkers such as malondialdehyde, hydroperoxides, carbonyl groups etc. are considered for research work.