Dear Muhammad Amin
You can find the various toxicity guidelines of OECD in oecd.org website.
Actual method and procedures will depend on your test material. OECD methods are accepted and practised worldwide as standard testing methods.
The (U.S.) National Library of Medicine's "ToxTutor" might be of interest to you, e.g., Section 5 is on Toxicity Testing Methods. Section 5's Learning Objectives are "After completing this lesson, you will be able to:
- Explain modern approaches to testing for and assessing toxicity.
- Identify sources of information related to alternatives to using animals to assess toxicity.
- Explain how clinical investigations and epidemiology studies are used to evaluate toxicity to humans."
"ToxTutor is a self-paced tutorial covering key principles of toxicology for users of the National Library of Medicine (NLM) chemical and toxicology databases."
https://toxtutor.nlm.nih.gov/05-000.html
https://toxtutor.nlm.nih.gov/index.html
In Europe, OECD methods are translated into "EU test methods". Upon adoption they are included in annexes to Regulation (EC) 440/2008 (latest consolidated version: http://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:02008R0440-20160304). You will find ample guidance on selection and interpretation of appropriate tests in the REACH guidance documents, specifically here: https://echa.europa.eu/guidance-documents/guidance-on-information-requirements-and-chemical-safety-assessment.
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