Dear all,
I am working on gene expression and Kaplan Meier curve dividing the patients in " high" and "low" using SPSS, then I want to do the cox proportional hazard analysis combining i.e the mutational status of one gene. I am naive in using SPSS Software How I can set up the analysis in order to find the Hazard ratio of specific combinations i.e X gene(high) and Y (gene) "mut" or "Wt".
Good Morning,
I've never used SPSS and the last time I used SAS for survival analysis was 20 years ago when I was still in University. It is relatively simple to set up a Kaplan Meier analysis in R using the Survival package. Granted, you have to learn a bit of code, but there are lots of resources available online to walk you through it. On the positive side, once you get your code working, you can re-use it, and, while it is more work at the beginning, you are forced to think about and understand your data and each step in the analysis, which leads to a better understanding of the outcomes. A good introduction tutorial on survival analysis using R can be found here: https://www.emilyzabor.com/tutorials/survival_analysis_in_r_tutorial.html
Good Luck!
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