Multiple charges in MALDI-TOF?

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Determination of partial specific volume?

Dear all, For some applications in AUC, we would like to correctly determine the partial specific volume of our biomolecules. We currently use Sednterp as a principal approach which diplays a...

06 July 2019 5,528 1 View

What condition should I use for analyzing intact protein on a MALDI Mass Spectrometer?

Hello, I am working on a biophysics core facility where we have developed a service to check among other things the molecular mass of the protein of interest, the presence of contaminants and...

04 May 2019 5,624 17 View

Bevacizumab intrinsic viscosity?

Hi all, Is someone knows the intrinsic viscosity of Bevacizumab? Best, Sébastien

10 November 2018 6,387 0 View

Why DHB is a reducing agent while sDHB matrix is not a reducing agent?

Hello everyone, My question is the next : Why the DHB matrix is a reducing agent while sDHB matrix is not a reducing agent? In this article it is written that sDHB is a non reducing agent Fast...

09 October 2017 6,687 4 View

Range of second virial coefficient

Hello, I would like to work with the second virial coefficient (A2 or B22) to determine the best conditions to formulate protein buffers and also to determine the best conditions for...

07 August 2017 9,086 3 View

Preparation of MALDI TOF experiment?

Hello everyone, I am new in the field of mass spectrometry and I have some questions about the preparation of the matrix and analyte for a MALDI TOF analysis. I prepared a saturated solution of...

09 October 2016 9,662 4 View

Refractive index increment of amoxicillin?

Hi, Is someone knows the refractive index increment of amoxicillin? Best, Sébastien

01 January 1970 2,157 4 View

How to learn more about SPSS and its Application?

I would like to learn more about SPSS and Its application especially in regards to data analysis. Please suggest me how I can learn more about it. Thank you so much.

11 August 2024 9,099 4 View

Can I base on reverse DNA sequences to perform alignment, convert to amino acids and GenBank submission?

I have reverse sequences (AB1 format), can I base on reverse DNA sequences to perform nucleotide alignment, convert nucleotides to amino acids and deposit the sequence in GenBank database?

11 August 2024 5,136 1 View

Can you connect an HPLC to a Mass Spec only at a certain time point?

Can anyone explain this method? Especially the last statement where it says only at 1.5 to 2.5mins was the MS/MS connected to the UPLC. How is that possible, is it a feature in this specific...

11 August 2024 8,140 3 View

Baseline drift in HPLC? What causes this?

Hello, Why do i see this baseline drift when i compare my blank (black) to the sample (blue)? Any suggestions as to why this happened? Thank you!

11 August 2024 3,769 4 View

Text-Communication from the M1 Hand Area using BCI—and then there is Elon Musk?

Willett, Shenoy et al. (2021) have developed a brain computer interface (BCI) that used neural signal collected from the hand area of the motor cortex (area M1) of a paralyzed patient. The...

10 August 2024 7,180 0 View

Has anyone applied Python in the field of textile engineering for data analysis, automation, or smart textiles?

I'm currently exploring the application of Python in textile engineering, specifically in areas like data analysis, process automation, and the development of smart textiles. I'm interested in...

10 August 2024 7,428 2 View

How can I use the cif data obtained from rietveld refinement extracted via gsas2, for microstructural analysis using ETEX software?

09 August 2024 7,718 0 View

GC-MS retention index prediticon?

Hello experts, Does anyone know any free software about retention index prediction ?

08 August 2024 7,402 2 View

How to calculate CCS for Sodiated adduct ions and Multiply Charged Ions?

I'm currently working on calculating the collision cross section (CCS) for various ions, and I'm facing challenges when dealing with sodiated and multiply charged ions. Most of the resources I’ve...

08 August 2024 8,328 0 View

How are iso-frequency contours plotted?

Let's say we have a standard, regular hexagonal honeycomb with a 3-arm primitive unit cell (something like the figure attached; the figure is only representative and not drawn to scale). The...

07 August 2024 1,936 1 View