I'm developing a theoretical case study involving a peds patient with acute lymphocytic leukemia...the patient achieved complete remission and is MRD-negative (sensitivity 1x10-6). During the active monitoring phase, would a pediatric hematologist order a BM biopsy every month for 6 months to track MRD status? This seems like a lot but I am not a clinician...any feedback is welcome
Azza Kamel
BM biopsy is not needed. The standard follow up is BMA and MRD according to the protocol
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Indu Thakur
Hi,
In UK, MRD is done at following time points only:
1. At diagnosis (to identify the molecular marker)
2. Day 28 (end of induction chemotherapy)
3. Week 9 of treatment
4. Week 14 of treatment
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