You should use headspace technique.

Check also my papers on DLLME for oxygen containing VOCs.

Regards

G

It is will be easy and very simple to use HPLC-RID instead.

https://www.researchgate.net/publication/228772964_A_simple_rapid_gas-chromatography_flame-ionization-_detector_GC-FID_method_for_the_determination_of_ethanol_from_fermentation_processes

Thank you all for your responses.

Grzegorz Boczkaj, I will look into the procedure of headspace technique and see if I can use it for my system.

Olga Mameeva, I know that, unfortunately we are not having the HPLC-RID facility under operation right now.

Jasim Al-saadi, thank you for sharing the article, I think it will be helpful for my purpose.

Regards,

SG

Balajii, the operational cost for GC comparing to HPLC is much lower!

Regards

G

Balajii,

you don't understand the question and purpose of the analysis.

Don't post statements that are not true (you should edit or delete your previous posts in this topic).

Everybody should care about quality and value of the answers.

regards,

GB

Dear Balajii Muthusamy,

Thank you for your response.

I understand that HPLC-RID method is so far most widely used technique for this kind of analysis. However, in some columns injecting aqueous samples are not allowed due to the moisture sensitivity of the column matrix. For direct injection, can you name a suitable column that will allow aqueous fermentation sample and will analyse Volatile fatty acids and alcoholic solvents simultaneously?

Regards,

Shiladitya