Demand for biologically active substance from natural raw materials has greatly increased in recent years, but key questions as to optimal complex and effective application thick needles extract from the green of pine and spruce remain unanswered. Efforts such as patent designs of the biologically active substance from the green of pine and spruce have provided a basis for international researchers and observing community to explore and compare different approaches. However, this synthesis effort has also highlighted important questions and challenges that remain to be addressed, first of all, obtaining the most optimal form with increased biological efficiency. After several years of our work at this cutting edge, it is time to move on to a more formal program based on our success with needles extract from the green of pine and spruce microencapsulation, refining and evaluating a number of different strategies to obtain the most optimal results.

Thick needles extract from the green of pine and spruce (TNE) is a product of pasty consistency, is a polycomponent (more than 300 components in natural proportions) biologically active substance with unique biological properties. TNE and a number of other secondary bio-products: residual coniferous mass, wax, essential oils are obtained from fresh woody greens of pine and spruce according to the original technology. TNE, using originally developed, at first pilot, later commercial industrial biotechnology, is transformed into a completely new microencapsular powder mass. To exclude losses and bio-activity, the paste product and the microencapsular powder mass are comparatively analyzed for composition and examined in vitro&vivo. Residual bio-products can be used to obtain bio-thermal insulation, heating pellets, bio-paint and varnish products.