Isoelectric point of DNA, mAbs, HCP: charecteristic slopes of the charge / ph Diagrams?

16 September 2019 0 5K Report

Hello,

are there any significant /characteristical differences between the curves of a DNA, mABs, HCPs charge and its ph-Value with respect to the slope and maximum charge values? Anyone knows any paper where those curves are compared? Would it be correct to determine the isoelectric point of an human IgG lying around 7 as a rough estimate for all groups?

Best, Dennis

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