We always read in papers and articles that natural plant extracts have antibacterial or in general antimicrobial effects so are these extracts lmpact the habitats of the microbiota of our body and if these microorganism develop a resistance against these extracts.
It may be possible for the Microbes to develop resistance against plant extracts. But, the beauty of the plant extracts is that they contain many phytochemicals which are known to exhibit antimicrobial potentialities, as such, the microbe can only develop resistance to one or more active phytochemicals at a time, but not the full array of all the plant's secondary metabolites. Moreover, each physicochemical has a specific way of inhibiting the growth of a particular microbe. Some are cell wall inhibitors, some are nucleic acid synthesis inhibitors etc. However, a single microbe cannot have the capacity to resist the mechanism of action of all the various phytochemicals in a given plant extract. So, development of resistance to the plant extracts may be difficult as long as the active phytochemicals are extracted using appropriate solvents
Thanks so much my colleague Mustapha for your Scientific anawer but if you have any Reference for the effects of different phytochemicals and if there are antimicrobial effects of natural extracts that is true for our gut microbiota that is meaning it will be affected by these phytochemicals when we use it as such or with food.
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