What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

Is there association of SARS-CoV-2 infection rate with meteorological factors?

There are contradictory research papers about the correlation between meteorological parameters and incidence of COVID-19 in some countries worldwide. Is there correlation between the...

15 February 2021 5,806 2 View

Why does the band sizes on Agarose gel electrophoresis differ from the peaks at capillary electrophoresis?

14 February 2021 4,773 4 View

How to calculate the Boiling point for metals at high vapor pressure?

In our experiment, some metal surfaces are exposed to radiation heat under high vapor gas pressure. I would like to ask if there is any way to calculate the boiling point for metals under high...

31 January 2021 249 4 View

What test should I use after a significant factoriual ANOVA?

Dear Colleagues Several resources recommended following significant interaction ANOVA with a simple main effect analysis to break down and interpret the interaction. I am wondering if I can...

29 December 2020 8,316 4 View

In your opinion , What is the percentage of demand for accountants and the percentage of stagnation ?

in your opinion , What is the percentage of demand for accountants and the percentage of stagnation ?

24 December 2020 5,349 3 View

How can increase the follower and citations of my articles?

I am looking for increasing the citations and reading my articles around the world.

13 December 2020 7,074 3 View

How to do energy optimization of charged molecule in gaussian?

when we want to study a reaction with a charged molecule (+) or (-) located on an atom, how do we optimize its structure with gaussian 09 thanks

29 September 2020 4,873 6 View

How can I do quantitive scoring for immunohistopathology(IHC)?

Is it enough inserting IHC image or quantitive details should be done, and how can I do this and what parameters needed ?

22 September 2020 1,881 2 View

Suggestion for the MS research topic?

hello everyone i have done work on NUMERICAL MODELING OF BRICK MASONRY in BSc. Now i want to carry the same/related work in MS too. i need your precious suggestions. Anyone having idea/topic...

14 September 2020 7,693 1 View

What is the difference between genotype and haplotype data in the ped format?

Hi everybody In the ped format for genotype, alleles of any SNP are represented by two columns (one for each allele, separated by a space). Is a column sufficient for the haplotype to...

27 February 2021 1,965 1 View

Are there any databases for gene co-expression or expression pattern clustering?

I am currently working on gene clustering based on co-expression pattern in mouse brain. The problem is I do not have some solid way to test my result. Are there any suggestions for databases...

22 February 2021 4,374 3 View

Useful architecture for bioinformatics?

Hi Dear researchers In ensemble-based architectural design Which algorithms are more useful for classification? What is the difference between parallel and ensemble architecture? Thanks I am...

08 February 2021 2,727 5 View

Electron density difference maps(Fo-Fc): what is the meaning of negative densities (red blobs)?

Dear community, As far as I understand, negative density features point at stuff that is in the model, but not supported by experimental data. However, in many cases (e.g. attached image), when...

06 February 2021 2,847 2 View

Qiime2- No reads passed the filter. How to set the trunc value?

Hi, I am working on some 16S sequencing data, and seems some of them are low quality. I am not sure how to set the trunc value in dada2. qiime dada2 denoise-paired \ --i-demultiplexed-seqs...

30 January 2021 6,213 3 View

Which software to use to statistically analyze Telomere Length_TRF_Southern Blot?

I am trying to measure telomere length in an ant species using the TRF method, which is a Southern blot technique. Currently, I am struggling with analyzing the images and would appreciate any...

29 January 2021 604 3 View

MHC Rabbit Genome Annotation? Domain annotation of each MHC Rabbit Gene?

I want to find a database(s) or a method where I can find and bulk download all the rabbit MHC genes and domain annotation. In humans using Ensembl, all MHC genes have names and domains but in...

28 January 2021 7,722 2 View

Best tool to build missing residues, minimize and validate a ligand model?

I am working on a ligand that is co-crystalized to parotein, but the ligand is missing some residues that makes it appear as if it was separated into two ligands! what I need is to connect them...

23 January 2021 3,975 7 View

What's the role of bioinformatics in poultry science?

bioinformatics has a big importance in human science and lots are seeking to study that field, so it attracts me to know it's relation with poultry science and how we can benefit from it in...

20 January 2021 6,963 3 View

How can I get the chromosomal location of a list of genes?

I'm looking for a bioinformatics website to get the chromosomal location of a radish gene id list, but in one shot instead of doing it gene by gene. Is there a way to do this? Thanks

17 January 2021 8,810 3 View