Is there any other feasibile solvent to extract bitespiramycin effectively?

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Yuri Mirgorod

Dear June Lee:

Bitespiramycin (BSPM; shengjimycin) is a group of 4"-acylated SPMs with 4"-isovalerylspiramycins(ISV-SPMs) as the major components, produced by

recombinant Streptomyces spiramyceticus F21 harboring a 4"-O-acyltransferase gene from Streptomyces mycarofaciens 1748. BSPM consisted of ISV-SPMs

I (7.4%), II (22.5%), and III (37.7%), the other minor components in BSPM include about 7 derivatives of SPM such as butanoylspiramycin and propanoylspiramycin.

BSPM has amino group and the radicals of organic acids.

Valeric acid test.

Best regards.

July Lee

thank you so much