You can use Patchdock (http://bioinfo3d.cs.tau.ac.il/PatchDock/) and Firedock (http://bioinfo3d.cs.tau.ac.il/FireDock/) for Pr-Pr interaction and do CoComap (https://www.molnac.unisa.it/BioTools/cocomaps/) for further analysis.

Try any following tools

standalone

Vina, PMV , PyRx, Chimera, Autodock tools etc

Online servers

Zdocking http://zdock.umassmed.edu/

HDOCK   http://haddocking.org/

Firedock http://bioinfo3d.cs.tau.ac.il/FireDock/

cluspro http://cluspro.bu.edu/login.php

Patchdock http://bioinfo3d.cs.tau.ac.il/PatchDock/

Best!!

Thank you @ Navneet and Anuraj...

Dear Akalesh,

The freely available software or server for protein protein interaction.

1. PPI-pred - http://bmbpcu36.leeds.ac.uk/ppi_pred/index.html

2. meta-PPISP -. http://pipe.scs.fsu.edu/meta-ppisp.html

3. cons-PPISP - http://pipe.scs.fsu.edu/ppisp.html

4. PINUP - http://sparks.informatics.iupui.edu/PINUP/

5. ProMate – http://bioportal.weizmann.ac.il/promate/

6. WHISCY - http://nmr.chem.uu.nl/Software/whiscy/index.html

7. ConSurf http://consurf.tau.ac.il/

8. InterProSurf http://curie.utmb.edu/prosurf.htm

Tools for validating protein-protein interaction binding energy

FastContact: http://structure.pitt.edu/servers/fastcontact/

Note:one thing keep in mind that all above mentioned servers/tools gives predictive results, in many cases it is found that  the findings of experimental protein-protein interaction does not match with predictive result. so, spend a lot of time to validate and interpret the result.

Thank u @ Mahadev Sir...

U may also try Hex

http://hex.loria.fr/hex.php

@ Soumitra thank u very much. I tried hex its a good software.