Hi,

your drug can working by inhibiting the polymerization of the fímbria but did not affect its expression. Also, other factors as flagelar genes and exopolysaccharide which also affect biofilm formation may be impaired after treatment with your drug. Best wishes.

fimbriae are essential for cell 's fixation.

fimbriae are essential for cell''s fixation. it is proteic structures also called adhesins for adhesion

you need proteases and or chelated substance like EDTA or NTA. you need also inhibit protein synthesis inhibition